1.plague的基本意思是“烦扰”,指因某事物〔原因〕使某人烦扰,也可指给某人〔事物〕造成麻烦或困难。
2.plague是及物动词,接名词、代词作宾语,可用于被动结构。

用作及物动词
▲S+～+n./pron.
Don't always plague your mother.不要总是缠着你母亲。
That mistake plagued him for years.那个错误使他痛苦了许多年。
She has been plaguing me with silly questions all day.她整天用愚蠢的问题烦扰我。
◇ 用于be ～ed结构
Why am I plagued with bad luck?我为什么老是倒霉?
She was plagued with arthritis.她患关节炎十分痛苦。
The system is still plagued by technical faults.这种系统仍为技术故障所困扰。
The construction schedule was plagued by the bad weather.天气恶劣使工程进度受阻。

plague还可用作名词,意思是“瘟疫; 麻烦, 苦恼; 灾祸”。例如：
Plague was then prevailing in that city.当时瘟疫正在该城流行。