irrespective常与of连用,构成复合介词。

They do whatever they like and are irrespective of the consequences.他们愿意做什么就做什么,从不顾后果。
Any person, irrespective of age, may join the club.任何人,不拘年龄,均可加入俱乐部。
He is going to buy it irrespective of what you say.不管你说什么,他是买定了。
They send information every week, irrespective of whether it is useful or not.他们每星期发出信息,不管是否有用。