1.frustrate的基本意思是“挫败”,即击败企图达到某一目的的人或挫败另一人的欲望。强调为此而作出的努力,而不管这种努力的大小或成败。
2.frustrate既可用作不及物动词,也可用作及物动词。用作及物动词时,接名词或代词作宾语,宾语可以是人或物,可用于被动结构。

frustrate in (v.+prep.)
(使某人)在…方面失败 fail in (sth)
▲frustrate sb in sth
He frustrated his enemies in their plans.他使敌人的计划落空了。
◇ 用于be ～ed结构
I'm feeling rather frustrated in my present job; I need a change.我感到现在干得很不顺心,需要换一换工作。
I was completely frustrated in my search for antiquities and a rare plant.我寻找古物和珍奇植物,但徒劳无益。

frustrate out (v.+adv.)
使…无法实现 make (sth) not be able to realize
▲frustrate sth ⇔ out
Heavy rain frustrated out our plans for a picnic.大雨使我们的野餐计划无法实现。

用作不及物动词
▲S+～(+A)
His trouble is that he frustrates much too easily.他的毛病是太容易泄气。
用作及物动词
▲S+～+n./pron.
But this didn't frustrate Einstein.He was content to go as far as he could.但这并没有使爱因斯坦灰心,他对能够更深入地研究而感到满意。
The police frustrated the bandit's attempt to rob the bank.警方挫败了匪徒抢劫银行的企图。
Illness frustrated his plan.生病使他的计划受阻。
The bad weather frustrated all our hopes of going out.恶劣的天气破坏了我们出行的愿望。
◇ 用于be ～ed结构
He was frustrated by his poverty.他因贫穷而灰心丧气。
He felt extremely frustrated when things went against him.形势对他不利时,他感到非常失望。

frustrate, baffle, balk, foil, outwit, thwart
这组词都可指使某人的计划、企图、希望等落于失败。它们之间的区别是:frustrate指使某人为实现自己的愿望或为达到目的所付出的一切努力付之东流; thwart指插在中间阻挠或挫败对方的意图; foil强调打破对方的计划,使其难以继续下去; baffle指用使人困惑的方法阻碍某人的计划得以实现; balk指靠设障碍来使某人的计划无法实施; outwit指靠机智胜过某人。